Role of Intracortical Excitability in Mal de Debarquement Syndrome
Research Planned at Ohio University-2011

The MdDS Balance Disorder Foundation will support a research study by Brian C. Clark, PhD, Director, Institute for Neuromusculoskeletal Research, Ohio University College of Medicine entitled, Role of Intracortical Excitability in Mal de Debarquement Syndrome. Dr. Clark and his team propose to determine if MdDS patients exhibit altered levels of cortical excitability when compared to age and sex matched controls.  The rationale for this proposal is based on a case study finding of an individual with persistent MdDS exhibiting high levels of intracortical facilitation as assessed using transcranial magnetic stimulation. If confirmed in others with MdDS, these studies will provide valuable details and an improved understanding of the neurological features of MdDS.  In addition to the primary aim, postural sway and assessment of vestibulosympathetic reflexes will also be assessed in all research subjects in this pilot study of 12 MdDS patients. Research subjects will receive compensation for their time but no travel allowances are included.  Dr. Clark is currently awaiting IRB approval from his institution and hopes to begin patient enrollment in early 2011.
If you have a confirmed diagnosis of Mal de Debarquement Syndrome and are interested in participating in this pilot research study Dr. Clark can be contacted or 740.593.2354