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Behcet's Disease

Timothy C. Hain, MD Page last modified: July 20, 2014

Behcets disease is a chronic systemic autoimmune disease characterized by chronic vasculitis of small vessels.

Signs and Symptoms:

The disease affects men and women to an equal extent. It may involve the pulmonary, gastrointestional, central nervous system, and cardiovascular systems.

Hearing is commonly impaired in Behcet's disease and rates vary between 24 to 62%. (Brama, and Fainaru, 1980; Evereklioglu et al, 2001; Gemignani al, 1991, Pollock et al, 2001; Sonbay et al, 2014 ). According to Kulahli, I., K. Balci, et al. (2005), the type of hearing loss is high-frequency sensorineural. ABR tests are generally not abnormal (Sonbay et al, 2014).

The literature also supports findings of frequent vestibular problems. (Cadoni et al, 2004; Choung et al, 2006; Evereklioglu et al, 2001, Gemignani al, 1991, Pollock et al, 2001). However, not everyone finds a high prevalence (e.g. Kulahli et al. 2005). Sugasawa, J. and S. Ishikawa (1986) suggested that there was high VOR gain. We think that this is more likely than not an error as it is simply not plausible that a multisystem disease should have any particular predilection for cerebellar VOR pathways.

Diagnosis

Behcets disease is based on recurrent oral ulerations together with at least two of the following: eye lesions, genital ulcers, skin lesions.

See also: Autoimmune Inner Ear Disease

References:

Copyright August 3, 2016 , Timothy C. Hain, M.D. All rights reserved. Last saved on August 3, 2016